{"id":941,"date":"2014-01-09T14:24:07","date_gmt":"2014-01-09T03:24:07","guid":{"rendered":"http:\/\/blog.panicola.com\/?p=941"},"modified":"2014-01-09T14:34:17","modified_gmt":"2014-01-09T03:34:17","slug":"bloodless-detection-of-malaria","status":"publish","type":"post","link":"https:\/\/blog.panicola.com\/?p=941","title":{"rendered":"Bloodless detection of malaria"},"content":{"rendered":"

AMAZING:\u00a0<\/strong>Able to spot single malaria infected cell among a million healthy ones without any false positives whatsoever…<\/strong><\/p>\n

http:\/\/www.medgadget.com\/2014\/01\/new-detector-reliably-spots-malaria-in-seconds-all-without-blood-draws.html<\/a><\/p>\n

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New Detector Reliably Spots Malaria in Seconds, All Without Blood Draws<\/h1>\n

by\u00a0EDITORS<\/a>\u00a0on\u00a0Jan 6, 2014\u00a0\u2022\u00a06:08 pm<\/p>\n

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\"malaria<\/div>\n<\/div>\n
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A laser pulse creates a vapor nanobubble in a malaria-infected cell and is used to noninvasively diagnose malaria rapidly and with high sensitivity. Credit: E. Lukianova-Hleb\/Rice University<\/p>\n

Malaria continues to be a persistent problem in large parts of the world and a great deal of effort has been spent fighting the disease. Yet, diagnosing malaria still requires a blood draw, reagents, and a trained medical professional to perform the test. Moreover, these tests are both labor and time intensive, making them difficult to offer in resource-poor environments.\u00a0Now a team from Rice University has developed a completely new test that doesn\u2019t require a blood sample nor a reagent to test whether it\u2019s infected by the parasite. Additionally, once developed into a product, the device shouldn\u2019t require a medical professional to do the testing.<\/p>\n

The system relies on a laser that creates \u201cvapor nanobubbles\u201d within infected cells. These bubbles eventually pop and create a signature sound that is acoustically detected by the device. In pre-clinical testing, the team showed that the device was able to spot single malaria infected cell among a million healthy ones without any false positives whatsoever.<\/p>\n

From the study abstract in\u00a0Proceedings of the National Academy of Sciences<\/em>:<\/p>\n

Here we show that the high optical absorbance and nanosize of endogenous heme nanoparticles called \u201chemozoin,\u201d a unique component of all blood-stage malaria parasites, generates a transient vapor nanobubble around hemozoin in response to a short and safe near-infrared picosecond laser pulse. The acoustic signals of these malaria-specific nanobubbles provided transdermal noninvasive and rapid detection of a malaria infection as low as 0.00034% in animals without using any reagents or drawing blood. These on-demand transient events have no analogs among current malaria markers and probes, can detect and screen malaria in seconds, and can be realized as a compact, easy-to-use, inexpensive, and safe field technology.<\/p><\/blockquote>\n

Study abstract in\u00a0Proceedings of the National Academy of Sciences<\/em>:\u00a0Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria\u2026<\/a><\/p>\n

Rice:\u00a0Vapor nanobubbles rapidly detect malaria through the skin\u2026<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

AMAZING:\u00a0Able to spot single malaria infected cell among a million healthy ones without any false positives whatsoever… http:\/\/www.medgadget.com\/2014\/01\/new-detector-reliably-spots-malaria-in-seconds-all-without-blood-draws.html New Detector Reliably Spots Malaria in Seconds, All Without Blood Draws by\u00a0EDITORS\u00a0on\u00a0Jan 6, 2014\u00a0\u2022\u00a06:08 pm A laser pulse creates a vapor nanobubble in a malaria-infected cell and is used to noninvasively diagnose malaria rapidly and with high … Continue reading Bloodless detection of malaria<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,9,7],"tags":[],"class_list":["post-941","post","type-post","status-publish","format-standard","hentry","category-cool","category-healthcare","category-technology"],"_links":{"self":[{"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/posts\/941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=941"}],"version-history":[{"count":3,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/posts\/941\/revisions"}],"predecessor-version":[{"id":944,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=\/wp\/v2\/posts\/941\/revisions\/944"}],"wp:attachment":[{"href":"https:\/\/blog.panicola.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.panicola.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}