Category Archives: healthy habits

Google’s Calico – extending health life years

  • Calico is about extending healthy life years, not just life
  • Larry Page’s view is that ageing is the cause and diseases are the consequence of this ageing
  • Google will use all data it has access to – from search terms, to location data and including genomic data when it becomes more readily available
  • Curing cancer is not as big an advance as you might think” saying it would only add about three years to average life expectancy.

Source: http://mashable.com/2013/10/24/google-calico/
S
ource: http://www.technologyreview.com/view/519456/google-to-try-to-solve-death-lol/

Google Wants You to Live 170 Years

BY DANI FANKHAUSER

Along the lines of self-driving cars and smart glasses, Google‘s newest venture promises to wow the tech scene. Only, it’s not quite tech, at least in the traditional sense. The venture is called California Life Company, or Calico for short, and its goal is to extend human life by 20 to 100 years.It sounds surreal, until consider that we already extended human life by 20 years over the past century. The average girl born today will live to be 100, a once outlying achievement.

Other research outlets have made relevant discoveries over the years, including worms thatdivide stem cells without aging and that resveratrol, found in red wine, seems to defend against diseases related to aging and could be manufactured as a more potent synthetic drug.

Meanwhile, companies such as Elixir Pharmaceuticals, Sirtris Pharma and Halcyon Molecular set out to extend human life, only to shut down (or be acquired, then shuttered by the buyer), many times running out of money before bringing a product to market.

Don’t be quick to assume Google’s involvement is strictly to benefit the common good, however. CEO Larry Page is pushing to spend on long term rather than incremental R&D. There’s money to be made here. The regenerative medicine industry is valued at $1.6 billion, and anti-aging products are virtually resistant to economic cycles. Therapies available today may be expensive,untrustworthy and could produce horrific results.

But one thing is true: The quest to live just a bit longer is in demand.

But living longer comes with its own challenges. One imagines doubling our elderly population and the strain that would put on their families and on resources in general. On the other hand, by allowing people to age slower, it’s possible a solution could extend our productive years, rather than the elderly years — so, an extra decade of being 30, rather than an extra decade of being 90 — a more attractive option for both individuals and culture as a whole.

Mashable spoke with experts in the space, who predict Calico will indeed approach the latter (Google declined to comment for this story). It won’t likely be one magic bullet solution, but rather, a group of solutions — a suite of products that will catch our imagination just as Google Glass and self-driving cars have.

The Problem With Aging

In a TIME profile, Larry Page said that solving individual diseases, even ones as pervasive as cancer, would not increase life expectancy by much. To reframe, cancer is the symptom; the true disease is aging itself. As we age and our cells wear down, it causes other old-age diseases.

Currently, much of our technology that extends life actually extends life in poor health, while thenumber of years lived in good health remains unchanged.

Our retirement age of 65 was originally set because hardly anyone ever reached that age.

“Today we spend an incredible amount [of money] out of keeping people alive in a bad state of health,”

“Today we spend an incredible amount [of money] out of keeping people alive in a bad state of health,” says Aubrey de Grey, chief science officer of the SENS Research Foundation, who presented a TED Talk on anti-aging.

This might explain why many people have no interest in living longer.A Pew study shows 56% of Americans would not choose to slow the aging process, even if such medical treatments were available.You may have read about the suicide of 60-year-old sports blogger Martin Manley. His website reveals his distaste for the physical and mental limitations of old age.But de Grey doesn’t expect a solution from Google to follow this trend, adding length to the “unwell” years of life while the number of healthy years remains the same.

“We will not be able to extend life without extending health,” he says. “Longevity is a side effect.”

Why Google?

For most of us, Google’s investment into longevity was a surprise (but note, Google will not be operating Calico, only backing it). Others already in the space were able to see the connection.

What Google brings to the table is data. “Not just one set of data, multiple forms,” says Harry Glorikian, founder of life sciences consulting firm Scientia Advisors. “Search data, GPS data, all sorts of other pieces, electronic breadcrumbs that you produce all out there to get a picture of you.”

This data could be paired with each person’s genome — a partial genome can be mapped today for $99 via 23andMe (another Google investment), but many are hoping a full genome will cost as much in the next few years.

Daniel Kraft, medicine and neuroscience chair of Singularity University, affirms that this will require people to relinquish some privacy, in hopes of helping others and themselves, but predicts it to be something many will do.

“Lot of folks will be happy to share elements of health history,”

“Lot of folks will be happy to share elements of health history,” he says.

For an example of how data can impact health, just look to Google’s Flu Trends, which predicted flu outbreaks based on search data, although it turned out to be accurate only in certain cases.

Finally, note that Google isn’t entirely new to this space. Singularity University has had a lot of cross-pollination with Google, Kraft says, and Ray Kurzweil, director of engineering at Google, is an advisor to Maximum Life Foundation, says founder David Kekich.

Glorikian notes that, much like how Google’s development of Glass inspired developers to create uses for it, the Calico announcement will bring further attention and energy to life extension.

“When one of these behemoths points to a certain place, everyone has to believe that there’s something there,” Glorikian says.

The Solution Won’t Be a Magic Pill

We won’t see an anti-aging product from Calico come to market in a year — it’s a long-term venture. The company is likely assembling a team (the announcement only mentioned leadership of Art Levinson, who is former CEO of biotech company Genentech) and deciding what kind of research to do. Of course, there are several types.

First, there is the idea of the engaged patient. You have the “ability to manage your prevention if you know the risk of certain diseases,” says Kraft. Again, think genome mapping.

Second, de Grey maintains that a medical solution will be discovered before a solution involving nanotechnology — and the medical solution will allow some of us to live long enough to also benefit from future solutions. A medical solution might involve cell therapy, gene therapy or injections. Nanotechnology could include tiny robots that repair our cells or assist organs.

Who Will Pay for It?

An early criticism of Calico was that it sounded like something that would increase the split between the rich and the poor, leaving millionaires to live as long as they like (a few extra years to spend all that money doesn’t hurt), while less privileged people would settle for traditional lifespans or shorter (many children in developing countries continue to die without lack of access to clean water).

The rich already have the option of cryonics, preserving their bodies after death in hopes future technology will revive them. It costs $200,000.

It is possible individuals will not need to cover costs of anti-aging treatments themselves? Much like health care today, it makes for a convincing job perk.

De Grey expects these solutions to be paid for by neither the individual or the employer, but rather, the government. Between social security and Medicaid, the government spends billions on treatment for old-age illnesses and providing for the aging population. Perhaps a product that slows aging will be seen as preventative care — over time, it may prove cheaper and could save government money down the road.

“These therapies will pay for themselves so quickly,” de Grey says.

Further Questions

An extra 100 years to live that you didn’t expect is a daunting idea. But because many of these solutions will piggyback over time, it’s not likely to be a sudden burden. As any technology comes to market, we as a culture must learn to use it both safely and with respect for others.

But still, asking the ethical questions is an important step. With an extra set of productive years, should people have second careers (or second marriages)? If you’ll be in this world for longer, does it reduce the drive to have children? Will a larger population mean more competition for resources?

A popular Steve Jobs quote communicates life’s brevity as a benefit to the human race:

“Death is very likely the single best invention of life. It’s life’s change agent.”

But even with increased lifespan, death is never too far away. When asked about the difference between solving death and solving aging, de Grey was quick to point out the obvious: “I’m not working on a solution to stop people from getting hit by cars.”

Thesis: Food composition is not as important as physical structure in determining satiety, and therefore overweight and obesity

vanishing caloric density: energy dense foods that meltdown rapidly in the mouth, often lack satiety (Dr. Drewnowski)

the problem with sugared soft drinks: energy consumed as fluid calories are not counted by the body as contributing to satiety, in the same way that energy consumed in solids.

Putting these two data points together, It would therefore seem that non-solid foods don’t satiate.

It makes sense that industry includes these forms of food in our diet, as the less satiety we experience, the more food we eat.

This also explains why fruit juice, but not solid fruit, leads to weight gain. It’s nothing to do with fibre slowing the absorption of calories in the gut, it’s to do with the satiating effects of calories derived from solids vs liquids.

This thesis makes sense in evolutionary terms, as the only pre-agricultural sources of liquid calories would have been honey – water being the mainstay.

New Jamie Oliver ministry to open in Sydney

Good to see this, aligned with Riot Health mission… potential partnering opportunity?

Source: http://www.goodfood.com.au/good-food/food-news/new-jamie-oliver-ministry-to-open-in-sydney-20131022-2vz6i.html

New Jamie Oliver ministry to open in Sydney

  • October 22, 2013
Passionate about encouraging people to eat more healthily: Jamie Oliver.

On a mission … Jamie Oliver is opening a Ministry of Food in western Sydney.

For many years Jamie Oliver has been on a crusade to fight obesity and bad eating habits, with the aim to equip people the world over with cooking skills and a greater appreciation of fresh food.

Sydneysiders have witnessed his mission through numerous television shows, campaigns and cookbooks. Now it’s closer to home, with the announcement of the first Ministry of Food centre in NSW.

The British chef will open a cooking school in August to teach basic kitchen skills. It will be at the Stockland Shopping Centre at Wetherill Park in western Sydney, which is undergoing a $222 million redevelopment. It will be Oliver’s fifth Ministry of Food kitchen in Australia.

“Obesity is not just a diet-related disease. It’s the biggest killer in Australia and what the Ministry of Food is, it’s a fix and response that really does transform people’s confidence in the kitchens,” Oliver said.

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The cooking classes, funded by the not-for-profit arm of electrical goods retailer The Good Guys, will focus on basic cooking skills, nutrition, budgeting, meal planning and shopping tips.

Oliver said recipes would be healthy and tasty and would include desserts.

“We all love ice-cream. Life is about ice-cream and sometimes people get confused with some of my messaging,” he said.

“Of course we want to be as healthy as possible but we don’t want to edit out things in life. Life is about having beautiful treats and cakes and things like that.”

He said the problems began when parents gave in to their child’s requests for more soft drinks and desserts. “That’s the sort of repetition that gets us into trouble. Absolutely I give my kids ice-cream but my wife is fairly strict about when and how much.”

This year, the Australian Diabetes Council revealed that a diabetes epidemic had gripped the western suburbs of Sydney, with Liverpool in the south labelled as the suburb with the highest number of people with the disease.

Of the 10 suburbs with the highest incidence of diabetes, seven were in Sydney’s west, said head researcher, Alan Barclay. This includes Liverpool, Mount Druitt, Campbelltown, Westmead and Blacktown.

The high rates could be drastically reduced with a combination of improved primary healthcare and better knowledge of healthy cooking, he said in July.

“People need to know more about food and how to prepare it,” Barclay said. “We have to start doing more in schools and in the local community.”

The co-host of Channel Nine’s Today show, Lisa Wilkinson, will be the ambassador of the Ministry of Food centre.

sharing drives behaviour change

http://medcitynews.com/2013/10/calico-communities-legislation-tech-drive-new-era-health/

  • peer support is a powerful model to support behaviour change
  • social media-backed sharing of progress reinforces achievements
  • Stevens is the CEO of KEAS > workplace health interventions

Calico, communities, legislation and tech drive a new era of health

October 14, 2013 12:45 pm by  | 0 Comments

America’s healthcare system has historically taken only baby steps to empower individual health and wellness ownership – until now. Recent events are about to alter existing healthcare paradigms and I believe this to be the most pivotal of moments. With Google’s Calico, the Affordable Care Act (ACA), Penn State’s wellness debacle and the rise of health-oriented social, healthcare entities are now taking a microscope to existing practices and infrastructures. What will they find? An industry destined for a radical makeover that will result in a prevention-based and consumer-driven healthcare network.

 Let’s take a look at the players involved, from the good (social networking and technology), the bad (Penn State’s wellness initiative) and the TBD (Calico and the ACA).

The Emerging Models
Legislation, technology, communities, and social networking are forcing a healthcare overhaul. Consider Google’s Calico: It has the opportunity to create the largest online community to share health information, turning personal health on its head. With a greater global consumer reach than any other organization, Google has the access and resources to throw at this opportunity, making it the ideal company to coordinate this effort – and being led by Art Levinson, the Bill Gates of biotech, doesn’t hurt.

Addressing the issue of aging in a share- and prevention-oriented effort is a response to the growing presence of the “empowered patient.” Calico could finally deliver on the promise for people to have the ability to seize proactive command over their health with a full understanding of their health data and risk factors. Previously constrained by outdated regulations and a healthcare system that doesn’t prioritize prevention, the tables are finally turning. The potential can live up to the hype.

The October 1 launch of ACA-mandated healthcare exchanges is another step toward preventative care and information sharing. While the ACA is polarizing on both sides, (the outcome of its execution remains yet to be seen) the core of the ACA will impact the resulting healthcare industry in a way that empowers individuals to own their well-being and fosters collaboration with all patient caregivers.

The Anti-Model 
Pennsylvania State University recently (and wisely) repealed a recent decision that established apunitive-based health and wellness program. Love or hate it, even the ACA agrees with the ‘carrot’ versus the ‘stick’ (companies can offer a reward of up to 30 percent of health costs for employees who participate in programs like risk assessment). Given the backlash and media attention Penn state received, it was an unfortunate way to learn what not to do.

Additionally, HIPAA is about to be a relic. Designed in a bygone era, HIPAA will be rendered obsolete thanks to the ACA. Because the ACA will provide benefits to those with pre-existing conditions, HIPAA’s privacy laws will only exist as roadblocks to individual health and wellness. The future of healthcare is driven by information sharing. It’s time for HIPAA to die

The Proven Models
Peer support in healthcare is proving to be wildly successful. As consumers, we increasingly seek the wisdom of crowds to create and sustain meaningful behavior change. El Camino Hospital in Mountain View, CA, recently launched a healthcare program for its employees in which social networking was a one of the tent poles in the program. During an 8-week time frame, over 1,000 participants lost over 1,000 pounds and began eating more fruits and vegetables. What was the number one motivating factor? Sharing progress updates with colleagues.

Today, 80 percent of healthcare costs are associated with preventable illnesses such as obesity, diabetes, hypertension and high cholesterol. It’s no wonder people are demanding to take back ownership of their health. Social networking, communities, technology and legislation are propelling old school healthcare into a consumer-driven and preventative-based model. I say bring it on — it’s about time.

NYT: The Challenge of Diabetes for Doctor and Patient

..or why managing diabetes doesn’t fit with how doctors have been taught, and therefore generally like, to treat patients >>> we need a radically new approach not involving doctors, busy doing other things – see Iora Health post re. health coaches.

The good news: lifestyle change for the obese or those with prediabetes may have lower progression to diabetes
http://archinte.jamanetwork.com/article.aspx?articleid=1485081

The average news: childhood obesity is plateauing [PN: ??from a scandalously high base]
http://www.nytimes.com/2012/12/11/health/childhood-obesity-drops-in-new-york-and-philadelphia.html?_r=0

The bad news: Intensive lifestyle change for diabetics did not reduce the risk of stroke or heart attack, even though these patients were able to lose weight, improve their overall quality of life, take fewer medications and even decrease costs.

Lifestyle changes — diet and exercise — require huge and ongoing investment efforts for patients; we’d like to think it pays off for the big-ticket clinical outcomes. Hopefully future studies will show benefits.

 

OCTOBER 17, 2013, 3:43 PM

The Challenge of Diabetes for Doctor and Patient

By DANIELLE OFRI, M.D.

My patient was miserable — parched with thirst, exhausted and jumping up to go to the bathroom every few minutes. His vision was blurry and he’d been losing weight the last few weeks, despite eating voraciously. I’d only just met him, but I was able to diagnose diabetes in about a minute. What was unusual was that this was a scheduled office visit; usually, patients with such overwhelming symptoms are the provenance of emergency departments and urgent care centers.

A quick shot of insulin and five glasses of water and my patient felt like a new man, with no need to go to the E.R. But now, of course, the hard work would begin. A new diagnosis of diabetes is an enormous undertaking — lots to explain, major life changes to contemplate, myths to dispel, consultations with a nutritionist and a diabetes nurse.

Two days later I had another new patient for a scheduled visit — thirsty, tired, losing weight, eating and drinking like mad, eyes so blurred he could hardly see. We’d barely gotten past the introductions before I’d made another new diagnosis of diabetes. Another shot of insulin, another five glasses of water, and then the plunge into the thicket of diabetes education.

Most of my regular office visits with diabetic patients — even newly diagnosed patients — don’t involve such dramatic presentations. More often the disease is found when we screen patients who have risk factors like obesity or a family history of the disease, or who have commonly co-occurring illnesses like hypertension, heart disease or elevated cholesterol.

These two patients highlighted the outsized role that diabetes plays in the primary care setting. The tidal wave of diabetes over the last two decades has made it one of the most common diseases that internists and family doctors treat. Right now feels like a good-news-bad-news time on the diabetes front, which in a general medical clinic can sometimes feel like the only front there is.

The good news is that childhood obesity rates have begun to inch downward in some cities, including among poor children, the first positive sign in the obesity epidemic in years. Obese children are potential future diabetic patients, so even incremental progress is a public health victory to celebrate.

Also good news is a study in which adults with obesity and pre-diabetes were able to lose weight with sensible lifestyle changes and coaching. This took place in a primary care setting, not a research setting, so this also suggests that we might be able to bend the curve of new diagnoses of diabetes.

But there’s also bad news. Intensive lifestyle changes for patients with diabetes, disappointingly, did not reduce the risk of stroke or heart attack, even though these patients were able to lose weight, improve their overall quality of life, take fewer medications and even decrease costs. Lifestyle changes — diet and exercise — require huge and ongoing investment efforts for patients; we’d like to think it pays off for the big-ticket clinical outcomes. Hopefully future studies will show benefits.

Even with all the research and new treatments available, combating diabetes can feel like a Sisyphean task. The bizarre contradiction of junk food being cheaper than healthy food, combined with a bombardment of advertising — especially toward children — make it a challenge even for motivated people to eat healthfully. Sugary drinks in monster-size containers abound. And our fixation with screens large and small keeps us increasingly sedentary.

But even with all the uphill challenges, there are successes, even if not perfect ones. Both of my patients who came to my office with florid diabetes that week have improved. Perhaps it was the concreteness of their symptoms that motivated them, but they have both made steady progress getting their diabetes under control.

Over the past few months they’ve been eating more moderately, and exercising more regularly. We’ve been calibrating their medications so that their blood sugars have left the stratospheric levels and are now only moderately elevated. Medication side effects, cost of glucose meter supplies, real-life logistics, and concomitant issues of blood pressure and cholesterol control have made it a challenge to get to normal. We’d still be dinged as “failures” in the quality-measures department for not achieving the recommended clinical goals, but both patients feel vastly better and are much healthier now.

So there’s bad news and good news. But the real news for these two patients – and for many, many more like them — is that diabetes is a marathon, not a sprint. Although there have been a flurry of life changes right now, diabetes is something they will live with for the rest of their lives. They will always have to be cognizant of what they eat. They will have to keep track of medications, glucose levels, carbohydrate intake, doctors’ appointments, exercise, and weight.  They will have to be on the lookout for the many complications that diabetes can bring. This of course is not news to anyone who has diabetes or treats diabetes, but for these two patients this was news.

Now, we gear up for the long haul, the messy, complicated, occasionally gratifying business of living with a lifelong chronic illness.

Dr. Danielle Ofri’s newest book is “What Doctors Feel: How Emotions Affect the Practice of Medicine.” She is an associate professor of medicine at NYU School of Medicine and editor in chief of the Bellevue Literary Review.

http://well.blogs.nytimes.com/2013/10/17/the-challenge-of-diabetes-for-doctor-and-patient

Social app puts bad habits to good use

Interesting, generalised, socially-mediated swear jar… another interesting addition to the habit-breaking arsenal…

Social app puts bad habits to good use

Social Rehub collects money every time users swear, or commit any other bad habit decided by their friends.

 

Bad habits are not only detrimental to the people that are chained to them, but can also be annoying for others. Acting as a digital swear jar, a new app from Romania — Social Rehub — collects money every time users blaspheme, or commit any other bad habit decided by their friends.
Multiple users can set up their own group of friends or colleagues who participate in the tip jar. Each individual can then be assigned a bad habit their friends get annoyed by — whether it’s swearing, smoking, biting fingernails or being late. Every time a friend catches a user transgressing, their tally goes up and they must pay the amount set by the group. The app also enables friends to snap a photo of the incident as proof. The collected money can then either be used to fund group nights out or sent to charity.

oleaginous

Simon Chapman (Medical Observer, 5 November, 2013):

“Big Tobacco is not investing in e-cigarettes to wean itself off cigarette sales,” he says.

“Its recent oleaginous rhetoric about them saving lives is utter duplicity. As with other forms of smokeless tobacco, Big Tobacco wants smokers to use e-cigarettes as well as cigarettes, not instead of them.

“Urged on by myopic health professionals who seem to have lost any population health focus they might have had, this may become one of the biggest blunders of modern public health.”

oleaginous
adjective
  1. 1.
    rich in, covered with, or producing oil; oily.
    “fabrics would quickly become filthy in this oleaginous kingdom”
  2. 2.
    exaggeratedly and distastefully complimentary; obsequious.
    “candidates made oleaginous speeches praising government policies”

AdShame saying stop, or we’ll say stop again?

A commendable element of a multi-prong approach… every bit helps.

adShame showcases the ways the alcohol and food industry regularly flout the rules when it comes to responsible advertising.

Our aim is to show that self-regulation is not working, and changes are needed to ensure that regulation protects children and young people from the harmful effects of alcohol and unhealthy food advertising. 

http://www.adshame.org.au/