Artificial sweeteners are alright by Pepsi…

  • they are safe in the “toxic” sense of the word
  • there is evidence that they help with weight loss along with other interventions
  • this all smacks of industry obfuscation – they’re not an essential dietary element, so don’t reference them as such

http://www.foodnavigator-usa.com/content/view/print/849807

Artificial sweeteners are safe and effective tools for weight management, says obesity specialist

By Elaine WATSON, 26-Nov-2013

Related topics: Sweeteners (intense, bulk, polyols), R&D, Food safety, The obesity problem, Health & Wellness, Beverage, Healthy Foods

While consumer concerns over artificial sweeteners have been blamed – in part – for the funk the diet soda market currently finds itself in (click here ), the fact remains that they are safe and effective tools for weight management, according to one obesity specialist.

Suzanne Phelan, PhD, associate professor in the kinesiology department at California Polytechnic State University and adjunct associate professor in the department of psychiatry, Brown Medical School, is an expert in the application of behavioral methods to prevent and treat obesity.

She is also co-principal investigator of the National Weight Control Registry, an ongoing longitudinal study evaluating 5,000+ successful weight losers.

People trying to manage their weight need to spend their calories wisely

Speaking to FoodNavigator-USA after contributing to a myth-busting session on low- and no-calorie sweeteners at the recent ObesityWeek conference in Atlanta, Georgia, Dr Phelan said that in an ideal world, we’d all just drink water to stay hydrated.

However, if people want something sweet, beverages using high intensity sweeteners can quench thirst without adding empty calories, she said, noting that people that successfully lose weight – and keep it off – are less likely to consume sugar sweetened beverages.

Long term successful weight losers consume smaller proportions of sugary drinks

No one food is to blame for obesity, and soft drinks companies are right that balancing calories consumed with calories expended is a key factor in weight management, she said.

However, achieving this balance is a lot harder if you regularly consume large amounts of empty calories from sugar sweetened beverages, she added.

On the firm’s latest earnings call, PepsiCo CEO Indra Nooyi said: “In the last 6-9 months, there has been an accelerated decline in diet drinks as people say they don’t want artificial sweeteners, they want more natural sweeteners, they don’t mind some calories. We are seeing a fundamental shift in consumer habits and behaviors.”

People trying to manage their weight need to spend their calories wisely and if you want to save calories, cutting out sugar-sweetened beverages and replacing them with water or beverages sweetened with low or no calorie sweeteners is a good way to do this.

“If you look at long term successful weight losers, they are consuming smaller proportions of sugary drinks – they are minimizing their consumption of sugary drinks and juices.”

(Click here to read about a recent Harvard meta-analysis showing that sugar-sweetened beverage consumption promotes weight gain in children and adults.)

No evidence that diet sodas make people crave sweeter foods or serve as an appetite stimulant  

Asked if she thought former NYC mayor Michael Bloomberg’s attempts to cap sizes of sugary drinks sold in certain outlets at 16oz were helpful, she said: “We should give initiatives like this a try. I’m in favor of government efforts to make it easier for people to consume fewer calories.”

As for the oft-quoted hypothesis that diet soda and other artificially sweetened products make people crave sweeter foods or serve as an appetite stimulant, there is “no evidence” to support this claim, she said.

(Click here  to read a 2010 review in the British Journal of Nutrition which found that “there is no consistent evidence that low-energy sweeteners increase appetite or subsequent food intake, cause insulin release or affect blood pressure in normal subjects”. A more recent study –click here –  published in the American Journal of Clinical Nutrition in Feb 2013 came to the same conclusion.)

Correlation, not causation

Meanwhile, a 2012 study also published in the American Journal of Clinical Nutrition (click here ) showed that replacing caloric beverages with non-caloric beverages was an effective weight-loss strategy, while a 2009 study co-authored by Dr Phelan in 2009 and published in the International Journal of Obesity (click here ) showed that those who have lost weight and successfully kept it off adopt a number of strategies, including drinking more artificially sweetened beverages, she said.

Dr Suzanne Phelan: People trying to manage their weight need to spend their calories wisely

So why do some commentators still insist that diet soda is responsible for all manner of problems?

For example, a recent opinion article published in the journal Trends in Endocrinology and Metabolism by behavioral neuroscientist Dr Susan Swithers alleged that regular consumption of diet sodas induced “metabolic derangements”putting users at “increased risk of excessive weight gain, metabolic syndrome, type 2 diabetes, and cardiovascular disease.”.

In the literature, there are some large scale epidemiological studies showing a correlation between consumption of low and no calorie sweeteners and increased risk of some of these health problems, said Dr Phelan, “so that has created a natural state of confusion.”

But this is correlation not causation, she said, and randomized controlled trials do not show similar results.

Meanwhile, a study by Harvard researchers published in the journal Circulation in 2012 (click here ) analyzing the Health Professionals Follow-Up Study, a prospective cohort study including 42,883 men, found that artificially sweetened beverage intake was not associated with increased risk of coronary heart disease risk.

The authors also said their results “highlight the need for cautious interpretation of studies reporting positive associations between diet drinks and cardiometabolic and cardiovascular outcomes”.

Artificial sweeteners and safety

As for safety, aspartame and sucralose are among the most thoroughly tested ingredients in the food supply and have been deemed safe by all major scientific and regulatory bodies from Health Canada to the FDA, the Joint Expert Committee on Food Additives (JECFA) of the World Health Organization (WHO) and Food and Agriculture Organization (FAO); and the European Food Safety Authority, added Dr Phelan.

emulin food additive addresses metabolic impact of junk food

  • who needs a healthy diet when you can fortify it with metabolic sensitizers? Mubadala does, and they want to put it in the food supply.
  • “It addresses the metabolic impact of both the milkshake you’re drinking and the cheeseburger you’re having with it”
  • It impacts on the glycaemic and metabolic impact of ingested junk foods by 30%
  • it apparently works acutely and chronically
  • it sounds like snake oil.. I hope Marc has run an interpol check on these guys
  • http://www.foodnavigator-usa.com/content/view/print/837344

Glucose management ingredient gets UAE distribution, ‘needs to be in food supply,’ founder says

By Maggie Hennessy, 25-Oct-2013

Related topics: Suppliers, Markets

Sometimes the best way to build a new market is to step back.

This is the case for ATM Metabolics, whose cofounders Dr. Daryl Thompson and Dr. Joseph Ahrens created Emulin, a patented blend of plant-sourced chlorogenic acid, myricetin and quercetin that claims to help maintain healthy blood sugar levels and facilitate weight loss in diabetics.

Facing hesitation from American corporations about incorporating Emulin into foods, the company has signed a licensing deal with United Arab Emirates development company Mubadala to distribute Emulin as both a medical food and as an additive to fortify diabetically sensitive food products. The firm hopes the distribution and resulting“dramatic improvement in glycemic management for type 2 diabetics,” who make up a growing percentage of the population in the UAE, will be a springboard to deploying Emulin as a medical food in the US.

“We need this to be in the food supply,” Thompson told FoodNavigator-USA. Emulin is currently available in the US as Diabetix, a dietary supplement supplied by VREV.

Blocks GI of the ‘whole meal’

Developed by ATM Metabolics cofounders Dr. Daryl Thompson and Dr. Joseph Ahrens, Emulin works by interrupting the metabolic pathways of carbohydrate metabolism. It claims to reduce glucose synthesis in the liver, enhance glucose uptake from the bloodstream, and increase the sensitivity of insulin receptors in the signaling pathways—thereby making insulin more efficient, according to Thompson.

What makes it so important for Emulin to be incorporated into food, he added, is it will not only block the glycemic impact of what you’re eating and drinking, but the whole meal. In other words, it addresses the glycemic impact of both the milkshake you’re drinking and the cheeseburger you’re having with it.

“Emulin when added to foods had the ability to reduce the entire glycemic impact and caloric impact of a whole meal by up to 30%,” he said. “This is because Emulin actually inhibits or ‘puts to sleep’ the enzymes in the body that are responsible for breaking down, transporting and storing sugars while inducing activity in metabolically useful enzymatics such as those in muscle tissue. Emulin reduces the amount of sugars that the body absorbs and at the same time enhances the body’s ability to utilize the sugars instead of storing them as fat.

“The good thing about this is that it is a ‘chaperone’ process that was developed by nature to properly regulate sugar transportation and usage in the human body. Our research team was lucky enough to identify this process and learn how to adapt it to our processed foods to make them safer glycemically.”

Thompson claims that Emulin works at both the acute and chronic level, meaning “the longer you take it, the less diabetic you become.”

Reeducating corporate America on ‘disruptive technology’       

The primary motivators for taking Emulin to the UAE were twofold: the growing incidence of diabetes in the UAE and the hesitance of American food companies to embrace new, disruptive technology in the diabetes realm.

The UAE has experienced remarkable economic growth in a relatively short period of time, which has raised the prosperity of its population. But this new-found wealth has also brought with it a growing incidence of metabolic syndrome and diabetes. According to the World Health Organization and International Diabetes Federation, 32% of the adult UAE population (age 20-79) may have diabetes or pre-diabetes, with other data indicating that the adult UAE population (ages 18 and above) has already reached a diabetes or pre-diabetes rate of 44%.

“The UAE is rife with diabetes and metabolic syndrome, but it also has a very forward-thinking healthcare system. And they’ve shown they really want to address this growing problem,” Thompson said. “We’re developing a plan there to get this distributed throughout the country and use it as model of how we will model foods here.”

The second reason for crossing the pond is the resistance of American food companies to embrace  “We’ve met with every American food company out there and the story is the same: they’ve gotten too big to be able to properly handle new disruptive technology,” he said. Thus, by spearheading the effort in the UAE, ATM Metabolics can demonstrate the practical approaches to dealing with metabolic diseases like diabetes with physical evidence. The product will be rolled out in the next six months, and Thompson expects to bring it back to the US within a year.

“We are working diligently to use UAE as a showcase to show how diabetes can be rapidly treated using Emulin in the food supply,” he said. “We’re hoping that this will serve as a blueprint for reeducating corporations here in the US.”

sugar-sweetened beverages and endometrial cancer

  • great to know Sugar Nutrition UK and Dr Glenys Jones are mouth-pieces for industry
  • non-causal association
  • questionnaire-based study

Sugar-sweetened drinks linked to higher cancer risk: Study

27-Nov-2013

Consumption of sugar sweetened beverages may be associated with an increased risk of developing endometrial cancer in postmenopausal women, according to new data.

Sugar-sweetened drinks linked to higher cancer risk: Study

By Nathan Gray+, 27-Nov-2013

Related topics: Carbohydrates and fibers (sugar, starches), R&D, HFCS, Beverage

Consumption of sugar sweetened beverages may be associated with an increased risk of developing endometrial cancer in postmenopausal women, according to new data.

The study, published in Cancer Epidemiology, Biomarkers & Prevention, revealed that postmenopausal women who consumed sugar-sweetened beverages were more likely to develop the most common type of endometrial cancer compared with women who did not drink sugar-sweetened beverages.

Led by Dr Maki Inoue-Choi from the University of Minnesota School of Public Health, the team found postmenopausal women who reported the highest intake of sugar-sweetened beverages had a 78% increased risk for oestrogen-dependent type I endometrial cancer (the most common type of this disease).

This association was found in a dose-dependent manner: the more sugar-sweetened beverages a woman drank, the higher her risk, the team said.

“Although ours is the first study to show this relationship, it is not surprising to see that women who drank more sugar-sweetened beverages had a higher risk of oestrogen-dependent type I endometrial cancer but not oestrogen-independent type II endometrial cancer,” said Inoue-Choi.

“Other studies have shown increasing consumption of sugar-sweetened beverages has paralleled the increase in obesity,” she added. “Obese women tend to have higher levels of estrogens and insulin than women of normal weight. Increased levels of estrogens and insulin are established risk factors for endometrial cancer.”

However, because the new study is the first to show an association between high sugar-sweetened beverage consumption and endometrial cancer, the findings need replication in other studies, Inoue-Choi explained.

Sugar Nutrition UK: This type of study has a number of significant limitations

Commenting on the study findings Dr Glenys Jones of Sugar Nutrition UK noted that the findings only appear to hold true for sugar-sweetened drinks, and not for glucose, fructose or  for sweets/baked goods.

“As the authors mention in the discussion, this type of study has a number of significant limitations and is unable to show any cause and effect relationships,” she added.

“A single questionnaire at the beginning of a study cannot account for any changes in dietary habits, reformulation or body weight during the subsequent 24 years of the study, all of which could be confounding factors in the statistical analysis.”

The American Beverage Association added: “This study does not show that sugar-sweetened beverage consumption causes endometrial cancer.  In fact, its findings conflict with the results of several other published studies that showed no association between consumption of sugar and risk for endometrial cancer. 

“The Mayo Clinic states common risk factors as changes in female hormones, older age, obesity, and inherited genetic conditions – not sugar or beverage consumption.  Moreover, the study only measured dietary behaviors at the very beginning of the study, yet makes conclusions about health outcomes over 12 years.”

Study details

Inoue-Choi and colleagues analysed data from 23,039 postmenopausal women who reported dietary intake, demographic information, and medical history in 1986, prior to the cancer diagnosis, as part of the Iowa Women’s Health Study. Dietary intake was assessed using the Harvard Food Frequency Questionnaire (FFQ), which asked study participants to report intake frequency of 127 food items in the previous 12 months.

The team explained that the FFQ included four questions asking usual intake frequency of sugar-sweetened beverages, including 1) Coke, Pepsi, or other colas with sugar; 2) caffeine-free Coke, Pepsi, or other colas with sugar; 3) other carbonated beverages with sugar, such as 7-Up; and 4) Hawaiian Punch, lemonade, or other non-carbonated fruit drinks.

‘Sugar-free soft drinks’ included low-calorie caffeinated and caffeine-free cola (for example Pepsi-Free), and other low-calorie carbonated beverages such as  Fresca, Diet 7-Up, and Diet Ginger Ale, said the authors.

The ‘sweets and baked goods’ category comprised 13 items in the FFQ, including chocolate, candy bars, candy without chocolate, cookies (home-baked and ready-made), brownies, doughnuts, cakes (home-baked and ready-made), sweet rolls, coffeecakes or other pastries (home-baked and ready-made), and pies (home-baked and ready-made).

Inoue-Choi and the research team then categorised the sugar-sweetened beverage consumption patterns of these women into quintiles, ranging from no intake (the lowest quintile) to between 1.7 and 60.5 servings a week (the highest quintile).

Between 1986 and 2010, 506 type I and 89 type II endometrial cancers were recorded among the women studied.

The team did not find any association between type I or type II endometrial cancers and consumption of sugar-free soft drinks, sweets/baked goods, and starch, but did find an association with sugar-sweetened beverage consumption after controlling for other lifestyle and risk factors.

“Too much added sugar can boost a person’s overall calorie intake and may increase the risk of health conditions such as obesity, diabetes, heart disease, and cancer,” Inoue-Choi commented.

Source: Cancer Epidemiology, Biomarkers & Prevention
Published online ahead of print, doi: 10.1158/1055-9965.EPI-13-0636 
“Sugar-Sweetened Beverage Intake and the Risk of Type I and Type II Endometrial Cancer among Postmenopausal Women” 
Authors: M. Inoue-Choi, K. Robien, A. Mariani, et al

Junk food trashes your memory

  • high fat/sugar affected rat memory
  • sugar water also affected rat memory in context of healthy diet
  • only took a week to manifest, prior to any weight gain
  • preliminary data suggests this phenomenon is non-reversible
  • hippocampal inflammation detected

http://www.sciencedirect.com/science/article/pii/S0889159113005758

18-Dec-2013

A new study has suggested that even a short-term diet of junk food can have a detrimental and damaging effect on the brain’s cognitive ability.

Human evolutionary biology and mismatch diseases

  • Book: The Story of the Human Body: Evolution, Health and Disease
  • Questions our culture’s overwhelming focus on treatment of symptoms instead of prevention
  • We’re adapted to put on fat, not lose it. We’re adapted to be physically active, not inactive

Type 2 diabetes a ‘mismatch disease’ for our Paleolithic bodies

21-Oct-2013

When we examine the long list of noninfectious diseases that trouble modern society—which run the gamut in severity from flat feet to acid reflux, anxiety, certain cancers, high blood pressure, obesity and type 2 diabetes—it helps to look back, way back, to the root causes to find answers, said Daniel Lieberman, chair of the Department of Human Evolutionary Biology at Harvard University.

Cool, automatic, calorie tracking standing desk

http://www.medgadget.com/2013/12/stir-kinetic-desk-tracks-calories-burned-and-helps-you-stay-fit-at-work.html

Stir Kinetic Desk Tracks Calories Burned and Helps You Stay Fit at Work

by GAURAV KRISHNAMURTHY on Dec 19, 2013 • 2:03 pm

smart desk Stir Kinetic Desk Tracks Calories Burned and Helps You Stay Fit at WorkThe latest fitness trend in offices around the country is employees giving up their chairs in order to stand while working. Now Stir, a Pasadena, CA company, is helping this fitness cause with their smart desk called Stir Kinetic that adapts to the user’s position and also helps track the additional calories burned due to standing.

tabld eside Stir Kinetic Desk Tracks Calories Burned and Helps You Stay Fit at Work

In order to start using the Stir Kinetic desk, the user has to first enter his or her standing and sitting heights, as well as the amount of time he or she would like to stand per day while working, using the touch screen console on the desk surface. The hardwood desk then uses motors to move its position from seated height to standing height by a mere double tap on the console. The smart desk tracks the amount of standing time per day in order to provide the user a count of the calories burned and has a Whisperbreath feature that automatically changes the desk’s height by one inch up or down, forcing the user to change positions, thereby incorporating some physical activity into office jobs.

The algorithm running the Stir Desk works to create changes in desk height at appropriate times and tracks the user’s work patterns to teach itself the best times to coax the user to change positions. The smart desk has been equipped with Bluetooth and WiFi connectivity to be able to transmit data to a smartphone in the future and Stir aims to roll out wellness and fitness smartphone apps that work with the smart desk.

The desk is currently available for purchase for a premium price of $3890, and comes in two top surface color options of either white lacquer or espresso-stained.

Six percent of strokes avoided by reduced salt intake – Netherlands

Six percent of strokes can be avoided by meeting sodium reduction recommendations: Study

18-Dec-2013

Achieving salt intakes in line with the recommendations may reduce stroke cases by 6%, but many consuming are still consuming way too much, says a new analysis from The Netherlands.