Wearables meets big data

Some see this as an opportunity to mobilise a peer-to-peer health knowledge commons outside the healthcare system that is filtered through government, hospitals and GPs’ surgeries. This new healthcare system would exist out among the public.

Pioneered by Tedmed’s clinical editor, Wellthcare tries to pinpoint the new kind of value that this people-powered healthcare system would create.

“Wellth” is closer to the idea of wellbeing or wellness than health; it is about supporting “what people want to do, supported by their nano-networks”.

A healthcare system that uses data we collect about ourselves would require these new bodies to make much bigger choices about how NHS trusts procure products and services.

Going back to the ever expanding market for wearable technology – with a potential patient group of 80m, there should be a lot more going on to turn our physiological data in the treasure trove it could be. Forget supermarket reward points and website hits, the really big data only just arrived.

 

http://www.theguardian.com/science/political-science/2014/jan/27/science-policy

Big data gets physical

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Tuesday 28 January 2014 01.05 EST
Can we make the rise of wearable technology a story about better health for everyone, not just better gadgets for me?
Smartphone app visualises two similar running routesSmartphone app visualises two similar running routesI am obsessed with my running app. Last week obsession became frustration verging on throw-the-phone-on-the-floor anger. Wednesday’s lunchtime 5km run was pretty good, almost back up to pre-Christmas pace. On Friday, I thought I had smashed it. The first 2km were very close to my perennial 5 min/km barrier. And I was pretty sure I had kept up the pace. But the app disagreed.As I ate my 347 calorie salad – simultaneously musing on how French dressing could make up 144 of them – I switched furiously between the two running route analyses. This was just preposterous; the GPS signal must have been confused; I must have been held up overtaking that tourist group for longer than I realised; or perhaps the app is just useless and all previous improvements in pace were bogus.My desire to count stuff is easy to poke fun at. It’s probably pretty unhealthy too. But it’s only going to be encouraged over the next few years. Wearable technology is here to stay. Smart phone cameras are also heart rate monitors. Contact lenses can measures blood sugar. And teddy bears take your temperature. A 2011 market assessment, estimated that there will be 80m sports, fitness and “wellness” wearable devices by 2016.

At the moment, it’s difficult to retrieve the data these systems collect. Nike only allow software developers access to data produced by people like me so they can create new features for their apps. I cannot go back and interrogate my own data.

Harbouring user data for product development is an extension of part of the search engine or mobile provider business model. When you log in to Gmail while browsing the internet, you give Google data about your individual search behaviour in exchange for more personalised results. Less obviously, when you use the browser on your phone, mobile companies collect (and sell) valuable data about what you are looking for and where you are. The latest iteration of this model is Weve, providing access to data about EE, O2 and Vodafone customers in the UK.

After Friday lunchtime’s outburst, I accepted that I’d never find the cause of my wayward run and quickly got absorbed back into the working day.

But I shouldn’t have.

We talk about the economic and social value of opening up government data about crime numbers or hospital waiting times. But what about the data we’re collecting about our daily lives? This is not just a resource for running geeks to obsess over, it provides otherwise unrecorded details of our daily lives. Sharing data about health has the potential to be an act of generosity and contribution to the public good.

For some areas of healthcare, particularly for type 2 diabetics or those with complex cardiovascular conditions, lifestyle information could make a huge difference to how we understand and treat patients. It could provide the kind of evidence badly needed to make headway in areas where clinical trials aren’t enough.

But it’s not yet easy to make something of this broader value created by fitness apps or soft toys with sensors in them. One person’s data is saved in different ways through different services – making for a messy, distributed dataset.

There is also no clear way to incorporate this into the current healthcare system. Some companies have made strides in that direction. Proteus Digital Health offers a system for monitoring a patient’s medication and physical activity using an iPad app and ingestible pills. This takes some much needed steps towards understanding how people comply with their prescription. At the moment, only 50% of patients suffering from chronic diseases follow their recommended treatment. If Proteus starts to sell information back to the health service, it will take digital health into mainstream healthcare. However,it hasn’t reached that point yet. And it is still a rare example of a company with the regulatory approval to do so. For example, Neurosky’s portable EEG machines, which measure brain activity, make excellent toys. But the company has no intention of certifying its products as medical equipment, given the time and expense it requires.

But does that matter? Neurosky’s wizard-training game Focus Pocus improves a player’s cognitive abilities including memory recall, impulse control, and the ability to concentrate. Some US medical practitioners are now prescribing Focus Pocus. This makes biofeedback therapy to ADHD patients available at home, replacing two to three hospital visits a week. This is going on anyway – outside the mainstream healthcare system.

Some see this as an opportunity to mobilise a peer-to-peer health knowledge commons outside the healthcare system that is filtered through government, hospitals and GPs’ surgeries. This new healthcare system would exist out among the public. Pioneered by Tedmed’s clinical editor, Wellthcare tries to pinpoint the new kind of value that this people-powered healthcare system would create. “Wellth” is closer to the idea of wellbeing or wellness than health; it is about supporting “what people want to do, supported by their nano-networks”. There is the potential for a future where we move from producers of data that is sucked up by companies into producers of data who consciously share it with one another, learn to interpret it and make judgments from it ourselves.

The current healthcare system may evolve to support this kind of change. In the UK, Academic Health Science Networks and Clinical Commissioning Groups provide new structures within the NHS that have the potential to support disruptive innovations. But so far these have led to small, incremental changes. A healthcare system that uses data we collect about ourselves would require these new bodies to make much bigger choices about how NHS trusts procure products and services.

Going back to the ever expanding market for wearable technology – with a potential patient group of 80m, there should be a lot more going on to turn our physiological data in the treasure trove it could be. Forget supermarket reward points and website hits, the really big data only just arrived.

Economist: Health and appiness

 

http://www.economist.com/news/business/21595461-those-pouring-money-health-related-mobile-gadgets-and-apps-believe-they-can-work

Health and appiness

Those pouring money into health-related mobile gadgets and apps believe they can work the miracle of making health care both better and cheaper

WHEN Kenneth Treleani was told last summer that he was suffering from high blood pressure, his doctor prescribed medicine to tackle the condition. He also made another recommendation: that Mr Treleani invest in a wireless wrist monitor that takes his blood pressure at various times during the day and sends the data wirelessly to an app on his smartphone, which dispatches the readings to his physician. Mr Treleani says the device (pictured), made by a startup called iHealth, has already saved him several visits to the doctor’s surgery.

Portable blood-pressure monitors have been around for a while. But the idea of linking a tiny, wearable one to a smartphone and a software app is an example of how entrepreneurs are harnessing wireless technology to create innovative services. By letting doctors and carers monitor patients remotely, and by making it simpler to collect vast amounts of data on the effectiveness of treatments, the mobile-health industry, or m-health as it has become known, aims to drive down costs while improving results for patients.

Many experiments are already under way in emerging markets, where new mobile devices and apps are helping relieve pressure on poorly financed and ill-equipped clinics and hospitals. But the biggest prize is America, which splashes out a breathtaking $2.8 trillion each year on a health-care system riddled with inefficiencies. The prospect of revolutionising the way care is delivered there is inspiring entrepreneurs. Mercom Capital Group, a consulting firm, reckons that of the $2.2 billion venture capitalists put into health-care startups last year, mostly in America, $564m went to m-health businesses.

The m-health market can be broken down into two broad categories. First, there are the apps and appliances used to monitor the wearer’s physical fitness. Firms such as Nike, Fitbit and Jawbone make wristbands and other wearable gadgets full of sensors that let people record their performance, and their calorie-burning, as they pound the pavement or sweat in the gym.

Second, other apps and devices link patients with a medical condition to the health-care system. Last month Google said it was working on a contact lens containing a tiny wireless chip and sensors that would measure and transmit the glucose levels in a diabetic patient’s tears. In December Apple was granted an American patent on a means to incorporate a heartbeat sensor into its devices.

Keeping an eye on glucose levels

The fitness apps may help people to keep up their training regimes, and in time make the population healthier. But in the shorter term they will not have much effect on the health-care system. Nor may they make many investors rich. IMS Health, a research firm, says that of the 33,000-plus health-related apps on Google Play’s app store (the figure for Apple’s iTunes is over 43,000), just five of them—of which two are calorie-counters—account for 15% of all downloads.

A growing posse of entrepreneurs think the big money is to be made in the second category, of apps and devices that seek to transform the way health care is delivered. Large companies spy an opportunity here too. Qualcomm, which sells wireless technology and services, has set up an m-health division, Qualcomm Life, and built a technology platform to make it easy for m-health companies to combine data about things such as the medicines people take and the results of tests they run on themselves, so their doctors can get a more complete picture of their health.

Among those firms with products already for sale, AliveCor makes a $199 gadget that attaches to a smartphone and lets patients take an electrocardiogram by placing two fingers on metal plates. It also sells a veterinary version for taking pets’ ECGs. The data are displayed in an app on the phone and can be reviewed (for a fee) by a cardiologist. CellScope, another startup, makes an otoscope—a device for looking inside the ear—that can be attached to an iPhone and an app that can send the images it takes to a physician.

Last year Medtronic, a huge medical-devices company, splashed out $200m to buy Cardiocom, which combines telehealth services with wireless home gadgets, including scales for heart patients for whom sudden weight gain may be a dangerous symptom. In October Verizon, a mobile-telecoms operator, launched a platform to transmit data from home devices, such as glucose monitors, to the firm’s secure “cloud” of servers.

As Don Jones of Qualcomm Life puts is, just as a car’s electronics tell a driver about its condition, so m-health devices and apps “give people dashboards, gauges and alarm signals” that make it easier for them and their doctors to track what is happening with their bodies. This may alert them to the need for action well before the patient’s condition deteriorates to the extent that he needs hospital treatment. Given that in America the average cost of a night’s stay in hospital is almost $4,300, there is scope for significant savings.

Another obvious way to use the technology to avert health crises is by checking that patients are taking their medicines. Propeller Health sells a device that fits on top of asthma inhalers, to monitor their use. Proteus Digital Health, which raised $63m last year, is testing an ingestible sensor that is taken at the same time as prescribed medication. The device, which relies on stomach fluids to complete a circuit to power it, transmits information to a smartphone so doctors and carers can track when a patient takes pills.

Again, the goal is to save money while improving health. The average annual cost of, say, treating sufferers from high blood pressure who fail to take their medicines is nearly $4,000 more than the cost of treating those who pop their pills reliably.

If such products live up to their promise, a side-effect may be that there is less need for medical technicians—an example of a wave of technology-related job losses that some economists expect. The development of machine intelligence, another hot area for investment (see article), may eventually mean there is less need for doctors or specialists to analyse test results.

One snag is that techies’ enthusiasm for such innovation is colliding with the health-care industry’s conservatism. Doctors in America have been paid for delivering more care, so products that might lead to fewer billable patient visits are viewed with suspicion. This is changing gradually as insurers switch towards rewarding hospitals for providing a better quality of care instead of simply paying them for the quantity delivered. But there is a long way to go in making the medical profession take an interest in cost-saving: a study last month in Health Affairs, a journal, found that few American surgeons had any idea of the cost of the devices, such as replacement hip joints, they implant in patients.

Encouraging iPochondria

Insurers may have cause to worry that, instead of reducing doctors’ workloads, the spread of m-health devices and apps may only encourage hypochondria: surgeries may be flooded with the “worried well”, fussing over every slightly anomalous reading. That may keep the medical profession nicely busy, but will not curb the ever-rising cost of health care.

So, to win over doctors, hospital managers and insurers, m-health firms will need to gather evidence to support their claims of cost-cutting and improved patient outcomes. Such evidence is still surprisingly scarce, says Robert Kaplan of the National Institutes of Health, a government agency. Stephen Kraus of Bessemer Venture Partners, which has examined hundreds of m-health startups, says many firms are blithely assuming that all you have to do is “appify” health care and the world will change.

Makers of more sophisticated m-health products, aimed at doctors, clinics and hospitals rather than patients, will have to build a sales force like that of a pharmaceuticals company, says Bob Kocher of Venrock, another venture-capital firm. That will take time and lots of money.

Some m-health products may have to win approval from America’s Food and Drug Administration. Most firms were pleased by a plan the FDA published last year that said it would regulate only those m-health products that do the work of a traditional medical device—an ECG, say, but not a pedometer. But applying for approval is still burdensome. And the FDA has not finished drawing up its rules: m-health firms are waiting for a framework on the use of information technology in health care from the FDA and two other agencies. Despite such obstacles, optimists such as Peter Tippett of Verizon see health care undergoing the mobile transformation that banking and other industries have already been through.

Andrew Thompson, Proteus’s boss, hopes that the sensors and software his firm is developing will form the dominant “platform” for m-health in the way that Facebook dominates social networking and lets other firms build apps that run on it. But it is likely to face stiff opposition. Mr Kocher thinks giants like Google and Apple may seek to build m-health platforms too.

Apple filed its patent for a “seamlessly embedded heart-rate monitor” after looking for ways to replace passwords with biometric methods—in this case, an ECG—to authenticate users. It may think carefully before entering a business as heavily regulated as medical devices. But it has made no secret of its interest in selling wearable gadgets packed with sensors; and if consumers prove as keen on m-health as investors currently are, it will surely want to satisfy them.

Firms that aspire to make serious money in m-health will need plenty of patience and deep pockets. But they may be able to rely on an army of technophile patients who lobby their doctors to incorporate the new devices and apps in their treatment programmes. Mr Treleani is one of them: “I’d be suspicious of medical practices that aren’t moving forward with these new technologies,” he says.

 

et tu vegetable oils?

  • vegetable oils cheap, but bad
  • advice should be to stop vegetable oils

http://www.raisin-hell.com/2014/02/cancer-on-rise-but-its-same-old-useless.html

Tuesday, February 4, 2014

Cancer on the rise, but it’s the same old (useless) prevention advice

According to a new report from the WHO (World Health Organisation), more than forty three thousand Australians died from cancer in 2012. And despite huge advances in treatment, it is now the single biggest cause of death in Australia. Prevention is clearly the key to changing that future. Unfortunately those charged with advising us are blind to the real cause of this lethal epidemic.
It’s an unfortunate reality but we all know someone affected by cancer. And most of the people we know neither smoke, nor drink excessively nor live obviously ‘unhealthy lifestyles.’ And yet they have all been cut down often in the prime of their lives.
It feels increasingly like we are being stalked by a silent and random killer. It feels like cancer is no longer something that some of us must worry about if we make it to old age. It feels like things are getting worse and they are getting worse quickly.
The latest report on Cancer from the WHO provides some hard data to support that feeling of unease. It reveals that in the nine years the report covers, cancer diagnosis in Australia increased by an alarming 14 per cent. In 2003, 274 Australians per day were diagnosed. In 2012, it was 312 people. Per Day! Worse than that, the authors of the report expect that number to almost double in the next twenty years.
Sadly having identified the problem, the advice on what to do about it is the same vapid nonsense that we have received for the last three decades. We should stop smoking, stop drinking and “maintain a healthy weight.”
In 2012, Lung cancer accounted for 8.9 per cent of Australian cancers and it is irrefutably the case that smoking is the cause for the vast majority of lung cancer cases. The good news is that the number of Australians smoking and consequently the incidence of lung cancer has been in steady decline since the early 80s. So while smoking clearly causes cancer it is not responsible for the rise in cancer rates in the last decade.
Equally, the studies show some level of correlation between alcohol consumption and rates of some cancers (notably mouth, throat and liver) but for most cancers the association is weak. Many studies are quick to point out that any harder evidence is difficult to obtain because most people drink alcohol (making it very difficult to find a non-drinking population for comparison).
Australians are no exception, being among the world’s biggest drinkers, but our level of consumptionhas not changed much at all in the last twenty years. We drank about 10 litres per person per year in 1994 and in 2008 we were drinking 9. Once again it’s statistically difficult to pin the rise in cancers on the booze.
When it comes to weight, the science is even fuzzier. The correlations between obesity and cancer are certainly there but viable explanations as to why are very thin on the ground. Even rarer are trials (try none) which control for all the other possible explanations (most notably that obesity is just a symptom of overconsumption of something else that feeds cancer, such as fructose).
But there is one aspect of human nutrition and cancer that has been studied using a double-blind, randomized, controlled lengthy human trial. No correlations. No guessing about explanations. Just one dietary change which lead to just one powerful conclusion.
The trial was conducted in the late 1960s. It involved randomly allocating men to diets that contained animal fat (let’s call them the butter eaters) or diets where that fat was replaced with vegetable oils (the margarine eaters). After eight years, the butter eaters had half the rate of death from cancer when compared to the margarine eaters. And that’s even though the butter eaters had a much higher proportion of heavy smokers. It’s that simple, use vegetable oils for fat and humans die much more frequently from cancer.
In Australia today it is impossible to buy processed food which uses animal fat. There is one simple reason for this. It’s cheaper. All our packaged food is infused with cheap vegetable oils rather than expensive animal fats and our consumption of those cancer causing oils has inexorably risen as a result. Knowing this, the rise in cancer diagnosis is not a surprise. Rather it is the inevitable result of the profiteering ways of the processed food industry. And it will continue to rise for as long as we continue to consume these oils.
I am not a conspiracy theorist. The processed food industry are not intending to kill us. But when it comes to a choice between their profit today and whether you die of cancer in eight years, guess which wins. The science on this is old. But that does not make it any less sound. Vegetable oils cause death from cancer and the sooner our health authorities acknowledge that and stop telling us mend our ways (and often, to consume more vegetable oil), the safer we will all be. They need to stop blaming the victim.

Greek yogurt waste a challenge and an opportunity…

Who knew Greek yogurt was so successful, but also so polluting!?

http://www.foodnavigator-usa.com/R-D/Greek-yogurt-waste-acid-whey-a-concern-for-USDA-Jones-Laffin

Greek yogurt waste ‘acid whey’ a concern for USDA: Jones Laffin

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By Mark Astley+

30-Jan-2014

Acid whey is a byproduct in the manufacture of Greek yogurt products including Chobani and Dannon Oikos. (Image: Chobani)

Acid whey is a byproduct in the manufacture of Greek yogurt products including Chobani and Dannon Oikos. (Image: Chobani)

Greek yogurt byproduct acid whey has become a significant concern for the US Department of Agriculture (USDA), says a company tasked by the agency to complete the development of technology to alleviate the issue.

In early 2012, the USDA’s Agricultural Research Service (ARS) established a cooperative research agreement with food industry innovation firm Jones Laffin to patent an “effective system for the economical and effective processing of acid whey.”

North Carolina-based Jones Laffin partnered with ARS to complete the agency development, which involves the extraction of whey protein and lactose from acid whey – a natural by-product of Greek yogurt, cream cheese, and cottage cheese production that is difficult to dispose of and can pollute waterways.

“The new process is an all-natural method of separating the component ingredients of raw acid whey – water, lactose, and protein – and turning them into valuable commodities which can be sold as ingredients in the food industry,” Joe Laffin, president of Jones Laffin, told DairyReporter.com.

The technology will “offer the dairy industry as opportunity to turn a disposal expense into a new revenue enhancement,” he said.

“The result is a new source of valuable, usable protein rather than an economic and environmental risk.”

“Problem of volume”

Greek yogurt is undoubtedly one of the biggest success stories in the food and beverage industry over the last few years. In 2007, Greek yogurt accounted for just 1% of total US yogurt sales. Now the product accounts for more than a third of all yogurts sold across America.

On the back of this growth, however, acid whey has become greater concern for the USDA, said Laffin.

“Acid whey is a really a problem of volume,” he said. “While it can be used in animal feed, its use must be limited. A chief danger is that, if it gets into waterways, it can result in massive fish kills and creation of a ‘dead sea’ effect by depleting oxygen.”

“Although these challenges could be met when the Greek yogurt industry was much smaller, they are now industrial level issues.”

“Since the disposal of acid whey has so threatened the growing Greek yogurt industry, we’re confident the technology will be critical to yogurt manufacturers, and the benefits will have a positive ripple effect not only on our national economy but also our national health,” said Laffin.

The company plans to introduce the technology, which will be suitable for “widespread commercial use”, in the second quarter of 2014.

Texturized whey protein

Through its partnership with the USDA’s ARS, Jones Laffin also boasts an exclusive license within the US and several European countries to develop texturized whey protein (TWP), which is the product of a process that converts whey protein into “a more functional ingredient.”

“Food manufacturers may utilize regular whey protein up to certain levels due to the very nature of protein as an ingredient,” said Laffin.

“TWP addresses those concerns by working in recipes and formulas at significantly higher percentages that traditional whey protein – doing so without altering the flavor, texture or other natural characteristics in products such as cereal, pasta, soups and beverages.”

The combination of the two processes being developed in partnership with the USDA should lead to the an increase in the production of “environmentally conscious, healthier commodities to address consumers’ growing needs and demands for products containing more protein,” Laffin added.

Soft drinks to tank despite natural sweeteners

Good insight into the machinations of the soft drink market in the US and elesewhere…

http://www.foodnavigator-usa.com/Manufacturers/Wells-Fargo-New-natural-sweeteners-won-t-save-ailing-soda-category/

Wells Fargo: New natural sweeteners won’t save ailing soda category

Wells Fargo: “We remain concerned about the ongoing deterioration of PepsiCo’s beverage business.”

Wells Fargo: “We remain concerned about the ongoing deterioration of PepsiCo’s beverage business.”

It’s been a grim year in the carbonated soft drinks aisles for the sector’s three biggest guns, but will things look up in 2014? And will new all-natural sweeteners reverse the downward trend in the diet soda sector?

In a series of notes to investors released as Dr Pepper Snapple Group, Coca-Cola and PepsiCo prepare to unveil their Q4 results, Wells Fargo analyst Bonnie Herzog said c-store retailers at least were convinced the answer to the second question is ‘NO’.

Given the importance that many beverage companies have placed on an all-natural sweetener as a means to bring consumers back to the carbonated soft drinks (CSD) category, going so far as to describe it as the ‘holy grail’, we asked our convenience store retailers whether or not they believed that this would have a positive impact if and when it’s introduced,” she said.

“Our retailer contacts [representing 15,000+ c-stores across the country] almost universally believe that an all-natural sweetener “won’t bring many consumers back” to the CSD category as “the damage may already be done.”

PepsiCo’s new Kickstart product is doing well in c-stores, but its core Diet Pepsi and Pepsi products have been struggling

One retailer told Wells Fargo: “Customer’s taste profiles/preferences have changed. As the group that was brought up on energy drinks gets older, carbonated soft drinks become less and less a part of their daily intake. This will eventually lead energy drinks to be a bigger part of the cold vault than CSD. In some areas, this has already occurred.

Another said: “Scary, units down in CSDs, seeing shift in drinking habits. Soft drink companies and contracts still trying to impose the old order, expect a big a shake-up if Q1 2014 looks anything like Q4 2013.”

Bad PR has not dented energy drink sales in c-stores

Meanwhile, despite all the negative PR surrounding energy drinks, c-store retailers remain bullish about their prospects, she said.

Our survey respondents believe that this year’s growth of 12.4% is greater than a year prior (12.1%), which we believe is a strong signal of a long runway of growth for the category for years to come.”

And space allocated to energy drinks – particularly Monster – is increasing, she said: “While the energy category today only comprises approximately 20% of our retailers’ shelves, our retail contacts think that over time, there is an opportunity to expand the energy shelf space by 50% to over 30% of total c-store shelf space.”

Sparkling Ice continues to go from strength to strength in the c-store channel

Finally, SPARKLING ICE continues to go from strength to strength, she said, while many c-store retailers also predicted strong growth in teas, sports drinks and protein-based drinks.

Dr Pepper Snapple Group: Many retailers say they might de-list TEN in the spring

Drilling down to the top three players in the category, Herzog is forecasting that full year (2013) volumes at DPS will be down 2% on flat revenues.

Meanwhile, the viability of the TEN low-calorie range remains in question, she said: “We are increasingly fearful that TEN may follow in the footsteps of countless other brand extensions that fail to become meaningful brands. We can only hope at this point that DPS discontinues any further investment to promote the platform.”

We remain concerned about the ongoing deterioration of PepsiCo’s beverage business

“We remain concerned about the ongoing deterioration of PepsiCo’s beverage business.”

PepsiCo, meanwhile, has seen “mixed results” as it has switched to an every-day-low-price (EDLP) pricing strategy in recent months, she claimed.

 “While we do believe that theoretically it is the right strategy, there has clearly been a negative impact on shares in measured channels.”

While recent launches Mountain Dew Kickstart and Frappuccino were  performing well, said Herzog, “We remain concerned about the ongoing deterioration of PepsiCo’s beverage business.”

While CEO Indra Nooyi has promised to announce ‘structural changes’ when she unveils the firm’s full year results on Feb 13, splitting the business down the middle was probably not on the agenda, however, Herzog predicted.

We don’t expect Senomyx to have an FDA approved, all-natural sweetener prior to at least 2015

But what about PepsiCo’s work on new sweeteners and sweet flavor modifiers?

San-Diego-based Senomyx has gone public about its tie up with PepsiCo on sweet taste modifier S617 and indicated that the first products from its collaboration will be commercialized this year contingent upon a GRAS (Generally Recognized As Safe) determination for S617.

However, progress on new all-natural high intensity sweeteners (which Senomyx is also looking at) is slower, said Herzog.

“We recently met with management from Senomyx… While Senomyx has several promising compounds that could offer sweetener solutions soon, and has made significant progress in an all-natural sweetener, we don’t expect Senomyx to have an FDA approved, all-natural sweetener prior to at least 2015.

Bonnie Herzog: “We believe Coca-Cola has been increasing its prices on carbonated soft drinks.”

“While we acknowledge that PepsiCo may source an all-natural sweetener from another company, or potentially develop it in house, we think Senomyx offers a good indication of the overall industry’s progress.”

Coca-Cola: We believe Coca-Cola has been increasing its prices on CSDs

At Coca-Cola, Herzog is forecasting volumes will be up 2% in 2013 with currency-neutral revenue growth of 1.9% when it unveils its results on February 18.

As for carbonated soft drinks (CSDs), said Herzog, “We believe Coca-Cola has been increasing its prices on CSDs but not on its still beverages as it continues to manage its business ‘for profits over sales in CSDs’.”

Natural sweeteners

While stevia is used in scores of high-profile brands from Sprite Select to Vitamin Water Zero, the only top-tier cola brands containing it are the Australian formulation of Pepsi Next, which has 30% less sugar; and Coca-Cola Life, which has 50% less sugar, and debuted in Argentina last year.

Neither Coke nor Pepsi has yet launched a zero calorie cola with stevia, however.

Speaking to FoodNavigator-USA last year, Jonas Feliciano, beverages analyst at Euromonitor International, said finding a natural sweetener that performs well in diet carbonates is not a panacea: “I just don’t think we’re going to see people drinking the volumes of Diet Coke or Pepsi that they used to, even if they reformulate. 

“The idea that carbonates can win back all the market share they are losing just by reformulating with natural sweeteners I think is missing the mark.”

Other commentators say the issue is not with the sweeteners, but the brands, pointing out that lightly carbonated Sparkling Ice has artificial sweeteners (sucralose), but is doing really well (click here ); while zero-cal carbonated soft drinks brand Zevia uses natural sweeteners (stevia and monk fruit) and is also doing really well (click here ).

Do fitness trackers work?

  • “If you want to change some behavior, whether it’s flossing your teeth, eating more fruits and vegetables, or getting more exercise, keeping a record of that behavior is a sensible place to start,” says Blair.
  • The activity tracker without counseling wasn’t enough. Only those who wore the tracker and received group and telephone counseling lost more weight—about 13 pounds more—than the control group.

http://www.nutritionaction.com/daily/diet-and-weight-loss/fitness-trackers/

Fitness Trackers

Can they help you lose weight?

 • January 29, 2014

 

Rupert Murdoch wears one on his left wrist. “This is a bracelet that keeps track of how I sleep, move, and eat—transmitting that information to the cloud,” the international media mogul told an audience in Sydney, Australia, last November.

“It allows me to track and maintain my health much better.”

Act now to download your FREE copy of Diet and Weight Loss: Trim Calories Per Bite to Trim Pounds without cost or obligation.

Personal activity trackers—like the Jawbone Up, Fitbit Flex, and Nike+ Fuelband—are the latest personal fitness gadgets.

“Some of them, like the BodyMedia armband, measure total energy expenditure, as well as intensity of activity and bouts of activity,” says Steven Blair, professor of exercise science at the University of South Carolina.

“If you sit for 10 minutes, and then get up and walk for one minute, it detects the different intensities and durations,” Blair explains. “It’s a more complex device that gets us closer to the truth than simple pedometers or accelerometers.”

Are activity trackers worth their price tag—from $10 for a step counter to over $100 for a more sophisticated armband?

“If you want to change some behavior, whether it’s flossing your teeth, eating more fruits and vegetables, or getting more exercise, keeping a record of that behavior is a sensible place to start,” says Blair.

A recent study hinted that activity trackers might help people lose weight.

Blair and his colleagues enrolled 197 overweight or obese middle-aged adults in a weight-loss program for nine months. Fifty received only a weight-loss manual (they were the control group), 49 got the manual plus an activity tracker to wear, 49 got the manual plus counseling sessions but no tracker, and 49 got the manual, the counseling, and the tracker.

The activity tracker without counseling wasn’t enough. Only those who wore the tracker and received group and telephone counseling lost more weight—about 13 pounds more—than the control group.

But for people who just want to know how physically active they are, “it’s not necessary to have a really complicated and sophisticated device,” notes Blair.

“A simple pedometer could tell you how many steps you’re getting. And if you’re getting 3,000 per day and you know that’s not enough, you can set a realistic goal of 1,000 more. And next week you can check to see whether you met that goal.”

Source: Int. J. Behav. Nutr. Phys. Act. 2011. doi:10.1186/1479-5868-8-41.

Bill & Melinda on Why We Give – Giving Tuesday

  • DonorsChoose.org
  • Heifer.org
  • Save the Children
  • World Vision

 

http://community.givingtuesday.org/page/billandmelinda#b11g14t20w13

Why We Give

By Bill & Melinda Gates

Thanks for taking a break from your holiday shopping to take a look at #GivingTuesday.

Everyone has their own reasons for giving back. For us, it’s simply about making the world a more fair and equitable place. We know we were very lucky to grow up where we did, when we did. We believe everyone deserves the chance to live a healthy, productive life. Those are the values we learned from our families, and they’re why we started our foundation.

In our work, we come across a lot of great organizations doing inspiring work in the U.S. and around the world. In fact, as we talked about #GivingTuesday, the hardest question we faced was, “Which groups should we highlight?” After a lot of discussion about all the great choices out there, we picked four.

When our children have a little extra money saved up and want to make a donation, they often turn to Heifer International and World Vision. Through Heifer, you can donate an animal to a community in need—a gift that can benefit the recipients for years afterward. Through World Vision and Save the Children, you can change a child’s life by helping provide food, health care, education and more. And DonorsChoose.org lets you help teachers meet their classrooms’ needs, enabling projects that might not happen otherwise.

Whoever you support, and however much you give, thank you for participating in #GivingTuesday. It’s a great way to help create the better world we all want. We wish you a happy holiday season.

  • Donors Choose.orgDonorsChoose.org is an online charity that makes it easy for anyone to help students in need. Public school teachers from every corner of America post classroom project requests on the DonorsChoose site, and visitors can give any amount to the project that is most inspiring.View More
  • HeiferHeifer International empowers families to turn hunger and poverty into hope and prosperity by helping bring sustainable agriculture and commerce to areas that need it most. The animals provide partners with both food and reliable income, as agricultural products such as milk, eggs, and honey can be traded or sold at market.View More
  • Save the ChildrenSave the Children gives kids in the United States and around the world what every child deserves—a healthy start, the opportunity to learn and protection from harm, especially when disaster strikes. When disaster strikes, Save the Children advocates and achieves lasting change for millions of children. They save children’s lives.View More
  • World VisionWorld Vision is dedicated to working with children, families, and their communities worldwide to reach their full potential by tackling the causes of poverty and injustice. World Vision works on every level to achieve the goal of child well-being—from international activism to checking in on children face-to-face.View More

Fresh food vending machine

 

http://www.fastcoexist.com/3025638/this-vending-machine-sells-fresh-salads-instead-of-junk-food

This Vending Machine Sells Fresh Salads Instead Of Junk Food

Chicago’s Garvey Food Court has a McDonald’s, a Dunkin Donuts and a vending machine that sells kale.

Each morning, the machine is filled with freshly made salads and snacks packed in recyclable jars. The ingredients, carefully layered to stay crisp throughout the day, are all organic, and locally grown when possible.

“I have always been someone who sought out healthy food, and I have been a bit obsessed with the food industry my entire life,” Saunders says. “I really noticed how hard it was to eat healthy when I was traveling a lot for work, and I started thinking about ways to give healthy food an edge in the market.”

By forgoing the rent and staff costs of a restaurant, Saunders can start to compete with the chains. He says he prefers the vending machines–which he calls kiosks or “veggie machines”–to selling the food in grocery stores, since the machines give him control over the user experience and distribution model.

“We are running pilot programs with a few stores, but at the end of the day I feel like having my own distribution channel gives me the flexibility to stay true to our healthy food mission,” he says. “I also felt like I could get the machines closer to the end user, which we believe is key to making it easier to eat healthy.”

Each of the vending machine’s offerings is carefully balanced nutritionally for the most health benefits. The “High Protein Salad,” for example, which includes quinoa and chickpeas, claims to offer more protein than many protein bars. The food is also always fresh: After discounting salads and snacks at the end of the day, the company donates any unsold meals to a local food kitchen.

The machine itself, clad in recycled barn wood, includes a small hole where users can return the jars for recycling. “It’s fairly low tech, and we occasionally find trash in there,” says Saunders. But at their newest location, he says they’re already getting a return rate of 80%.

So far, almost everyone who tries the food comes away a fan. “As far as I know we are the only vending machine in the world to have Yelp reviews,” Saunders says. “Most people tell us that the salads are the best they have ever had.”

“All of the food we serve from our machine has to be in the running for the title of ‘Best ______ I have ever had,'” he adds. That means some items, like sandwiches, will never be on the menu, because they just can’t be as good when they aren’t freshly made. But salads are different, and the company is constantly testing new recipes to add.

After opening two more vending machines last fall, Saunders says that Farmer’s Fridge is continuing to quickly grow. “I am not sure where we will stop, but at this point we have more machines planned to launch in February than I thought would launch in all of 2014.”

On wearables

The point isn’t the gadget: it’s the combination of the intimacy of a device that is always with us and that only we use, with the power of cloud-based processing and storage. The wearable device itself is actually only the small, physical manifestation of a much larger service: Google Glass gives its wearers a head-up display, voice control and a forward-facing camera, but it’s only through a connection to the internet that it can live up to its potential

“He put this engine into our ears,” wrote the Lilliputians, in Gulliver’s Travels, Jonathan Swift’s 1726 classic, “which made an incessant noise, like that of a water-mill: and we conjecture it is either some unknown animal, or the god that he worships; but we are more inclined to the latter opinion, because he assured us, (if we understood him right, for he expressed himself very imperfectly) that he seldom did any thing without consulting it. He called it his oracle and said it pointed out the time for every action of his life.”

Just as Gulliver’s Travels was a satire, and its description of his watch essentially a tease on time-based affairs, so too we are starting to find that the accoutrements of our modern communications are ripe for mickey-taking. The Bluetooth headset has gone from a status symbol to the mark of a tosser. There’s a Britishness to this — a who do you think you are to need such a device? thing. There’s also a feeling of enslavement that might be hard to shake. Just as our culture turns towards reducing the digital distraction in our lives, will we really want to be cuffed to our inbox? It’s said that in a ham-and-egg sandwich, the chicken is involved but the pig is committed: just how committed to our communications do we want to — or want to appear to — actually be?

“It’s not information overload. It’s filter failure.” Clay Shirky

http://www.wired.co.uk/magazine/archive/2014/01/features/the-third-wave-of-computing

Wearables: the third wave of computing

TECHNOLOGY

23 JANUARY 14  by BEN HAMMERSLEY

Dan Matutina

This article was taken from the January 2014 issue of Wired magazine. Be the first to read Wired’s articles in print before they’re posted online, and get your hands on loads of additional content by subscribing online.

Wearables are truly upon us. It takes about a decade to shift: from the basements of the 70s, to the desks of the 80s, the laps of the 90s, the front rooms of the noughties and pockets of the twenty teens, the location of hot computing — the place where the most interesting developments are happening — always moves and shrinks with every generation. And although this decade is all about the smartphone, today we’re starting to see the path to the next stop in this constant progression: if not in, then definitely on the body.

As we’ll discuss, this leap, from the situated and leave-behindable to the always-on, always-present, always–connected, is not without its drawbacks. But it also promises a near-future world of self-knowledge, sensors and superpowers. Even today we can monitor our activities and compare ‘n’ share with our friends via devices such as the Nike+ FuelBand, the Fitbit or the Jawbone UP; and we can bring information, alerts and alarms to our wrist with devices like the Pebble watch. Coming devices will give you head-up displays, vibrating interfaces, speech recognition and a constant –understanding of where you and it are in time and space. By smearing the interface between –yourself and the internet across your nervous system, wearables are the first step in augmentation of the human. They give us superpowers in the same way cybernetic implants do to the heroes of science fiction.

The point isn’t the gadget: it’s the combination of the intimacy of a device that is always with us and that only we use, with the power of cloud-based processing and storage. The wearable device itself is actually only the small, physical manifestation of a much larger service: Google Glass gives its wearers a head-up display, voice control and a forward-facing camera, but it’s only through a connection to the internet that it can live up to its potential.

And what potential — never forget a name again, thanks to its camera, facial-recognition tech and a link to your social networks. Never be lost, through the map hovering in the corner of your eye. Develop an instant expertise in the art you’re looking at with a reverse image-search and a Wikipedia lookup. Have perfect memories of everything you do, say, see or hear through a constant archive of point-of-view shot from your forehead. Be a more scintillating conversationalist by recording, transcribing and automatically Googling everything you hear. Link your devices and adjust your day’s agenda to match your pulse-rate-monitored stress levels. Receive an ambient alert to your wrist whenever you’re close to something that’s on your phone-stored shopping list, and whisper to your glasses to show you where it is on the shelf. Feel a tingle in your pocket when you walk past someone whose OKCupid profile matches your own, and whose biomonitoring devices -indicate is in a receptive mood. Automatically plot a route to work that takes you past breakfast places whose menus match your immediate biochemical needs, and have this hover in front of you as you cycle, with warnings for when you’re pedalling too hard for your heart, and notifications of upcoming meetings being cancelled, as you sub-vocalise acknowledgements in English, having them translated in real-time into the Japanese of your colleague’s wrist-bound diary.

Many of these scenarios are dependent on different devices, from different manufacturers, successfully talking to each other: for wearables to sing the body electric, they must first form choirs. Rival firms will have to adopt compatible standards and allow for truly open development before the more advanced ideas are possible. But these are engineering and business decisions. More important for wearables, with their curious mix of the intimate and the public, is the social reaction to their use.

The surest sign of a technological niche about to be filled is an outbreak of Apple rumours. No other firm produces such a flurry of speculation, guesswork and extrapolation of minor signals as Apple. The iWatch (name by popular consensus) has never been mentioned by anyone from Apple, nor has anyone from its supply chain spoken of it or leaked any details, but nevertheless there are signs  that such a thing might be on its way.

Apple has a handful of patents that look useful, plus there are a few details in the new iPhone and iOS that would make a lot of sense if an iWatch existed. The iPhone 5s has a chip dedicated to monitoring its owner’s movements, making it in essence a pocket-carried FuelBand, which shows that Apple is at least paying attention to the quantified-self idea. And iOS7 has a feature, iBeacon, which allows for communication with low-powered devices using the newest Bluetooth standard. That would be very useful over the range between your pocket and your wrist. Siri, the voice interface on iOS, would be splendid on a wearable, and the iOS notifications screen looks eminently transferable. But all of this is, of course, entirely conjecture. The beguiling/tiring axis of Apple product fantasies is subject to the traditional Apple announcement-and-launch schedule, and the likely slot for the Next Big Thing is the mid-January keynote, just in time to make everyone look mournfully at their month-old but now painfully past-it Christmas presents.

Like many internet technologies, wearables are very much a product of the environment in which they are funded and designed, primarily that of Silicon Valley — both the physical place and its thought-construct offshoots around the world. Invariably, the use-case scenarios for wearables both address problems that are two degrees away from behaviours not already invested in, and furthermore take a technofundamentalist position on existing social norms.

To think about this, consider that there are two classes of wearables today: the introspective, which monitors what you do and where you go, and informs you of changes to the state of your body and expanded self in cyberspace; and the extrospective, which looks outwards, to monitor and record the world around you. A Nike+ FuelBand is introspective. A Narrative Clip cam, which takes pictures constantly as you wear it, is extrospective. The introspective is of no concern to others. Who cares if you’re counting your steps? But the extrospective is a different beast. Society has yet to evolve the correct etiquette for having a meeting with someone who is constantly recording and archiving their conversations, or for going to a party with someone whose necklace is uploading pictures of you to the cloud every 30 seconds. It is as hard to imagine future generations’ views on these things as it is today to understand the Victorians’ erotic desire for table legs. But today’s society might find it challenging, if not already illegal, under different countries’ privacy laws. You may be able to remember the faces of all the people you meet, but use a device to capture them automatically and put them into a database, and a line is being crossed — even if that data is inaccessible to others. Whether that line demarcates violating others’ privacy — or breaking your own sense of non-augmented humanity — is something we will have to hash out.

Some wearable technology has already developed a level of understood etiquette. A glance at your watch in the middle of a meeting is rude. But it’s also an action that is understood by the person you are meeting: you wanted to know the time. Wearables, especially those with displays that cannot be seen by others, go much further than this. You may be aware that the other person just interacted with their device, but you have no idea what that interaction was. As interfaces become more ambient, or more fluid, the social meaning of interacting with them mid-conversation becomes more confused and potent. Today’s one-on-one conversations might be tomorrow’s one-on-one-plus-her-fact-checking-AI conversations. Just what did that mid-conversation microdistraction mean? That your lies have been found out, or that their football team just scored? It will be unnerving.

Valley-based technologists, however, may take the more fundamentalist view that it is not their technologies’ place to deal with human insecurities, but rather society’s job. The ideology of what it is possible to do with the technology is paramount, and human squeamishness has no role to play: a sort of device-led fait accompli. This is already happening, for example, in the concerns expressed around the supposed inability of the digital world to forget youthful indiscretions, prompting the then CEO of Google, Eric Schmidt, to suggest that in the future, people might change their name at a certain age to reset their online identity. Wearables could accelerate this process.

The social and the technical are inevitably interlinked. Although wearables have themselves been enabled by advances in chip design and component miniaturisation, it is perhaps that relentless technological progress that precedes their downfall. There is an old joke in software design that all programs expand until they can receive email. Likewise, we might suspect that all tiny devices will upgrade until they are general–purpose computers. This has already happened with phones — the iPhone 5S is purportedly as powerful as a MacBook Pro from 2008 — but phones can be put away, or obviously turned off. A wristband that today might be expected to just count your steps could, in theory, be programmed to record all that happens around it, upload that data to the cloud and do something mysterious with it. We are never sure about how new technologies will be received, and history is full of examples of our willingness to accept new deskbound technologies. Wearables, –however, push tech into the fields of fashion, of social signifier and public display. At your laptop, in private, you’re hard to judge. Use these technologies in public, and they enter a different realm.

“He put this engine into our ears,” wrote the Lilliputians, in Gulliver’s Travels, Jonathan Swift’s 1726 classic, “which made an incessant noise, like that of a water-mill: and we conjecture it is either some unknown animal, or the god that he worships; but we are more inclined to the latter opinion, because he assured us, (if we understood him right, for he expressed himself very imperfectly) that he seldom did any thing without consulting it. He called it his oracle and said it pointed out the time for every action of his life.”

Just as Gulliver’s Travels was a satire, and its description of his watch essentially a tease on time-based affairs, so too we are starting to find that the accoutrements of our modern communications are ripe for mickey-taking. The Bluetooth headset has gone from a status symbol to the mark of a tosser. There’s a Britishness to this — a who do you think you are to need such a device? thing. There’s also a feeling of enslavement that might be hard to shake. Just as our culture turns towards reducing the digital distraction in our lives, will we really want to be cuffed to our inbox? It’s said that in a ham-and-egg sandwich, the chicken is involved but the pig is committed: just how committed to our communications do we want to — or want to appear to — actually be?

As timepieces, wristwatches have been generally replaced by the clock on your phone. But that notwithstanding, a cheap digital watch keeps the time as well as the most expensive chronometers. Spending more than £5 on a watch is not a decision of practical use: the men’s watch market, for example, is now almost entirely one of fashion, of signifiers of wealth, of male-accepted jewellery — either that, or wine bars are popular with deep-sea divers.

But that market is based entirely on notions of craftsmanship, tradition and symbols of supposed manliness that are notably absent with the sort of wearable technologies we’re talking about here. Equating rapidly innovating devices with luxury misses the point of either: you can stick jewels to something, or you can make it super rugged, but neither of those will take away from the fact that they are functional devices, soon to be declared obsolete and upgraded. They’re built to do a job; on the nature of that job will you be judged — and that job might be nerdy.

The slow roll-out of Google Glass is a case in point. It is undoubtedly amazing technology and there are plenty of use-cases for wearing it while doing something else. But even before anyone had seen it in the wild, there was a word for people wearing it casually around the place: “glassholes”. Already dubbed “a Segway for the face”, Google Glass may turn out to be the most useful thing ever, but wear it all the time and you’ll be put into the same social slot as people with shoulder-holsters for their BlackBerry.

Ultimately, though, that’s a question of marketing and the transformation of social norms. So too is our commitment to our data. The recent fashions of unplugging, digital detoxing, email fasts and screen-break sabbaths have highlighted the desire of many to be free from the constant flow of information. As an activity that happens in front of a large, special-purpose machine on our desks, this feels like work, even when it’s play.

The limitations of the devices might be their, and our, saviour in this regard. As NYU professor and writer Clay Shirky says, “It’s not information overload. It’s filter failure.” Perhaps the limited size of the display, the cruder signalling from a wearable device, will encourage developers to refine those filters. If all you can display is a few lines of text, or if it’s one vibration for left and two for right, then the filtering will need to be done by the system, and not by the user. The stupid device being the pointy end of complex software places the responsibility for technological sophistication back into the laps of the programmers and designers.

Wearable technologies promise a great deal. For the individual, their usefulness, their very intimacy, offers a levelling-up of personal ability and self–understanding. One app that already exists for the iPhone, Word Lens, offers real-time translation of printed text, such as street signs, in the video camera, laid over the original text. That or something like it will be a Google Glass app sooner or later.

The barrier between the internet and the rest of the world is weakened by wearables, and their technology is no longer a personal matter. Using them might prove to be — in circumstances of extrospection, or of massive–augmentation of personal ability — considered socially unacceptable, unfair or just uncool. How that social progress plays out will be just as interesting as the technology itself. Personal computing is no longer personal. We will wear it like we wear our heart: on our sleeve.